INTELLECTUAL PROPERTY

The Targa Therapeutic Payload technology is protected by numerous patents and applications. The most important issued ones are:

Rosenblum MG, Aggarwal BB, Kohr W. Primary protein structure of the plant toxin gelonin and recombinant methods for production of fusion protein conjugates comprising gelonin and gelonin fragments.
Patent No.5631348, Issued May 20, 1997.

Rosenblum MG, Beattie KL. DNA sequence encoding gelonin polypeptide.
Patent No. 5624827, Issued April 29, 1997.

Rosenblum, et al. Protein sequence of the plant toxin gelonin.
U.S. Patent RE37,462, Reissued December 4, 2001.

Rosenblum MG. Immunotoxins directed against CD33 related surface antigens.
U.S. Patent 6,599,505 Issued July 29, 2003.

Targa has reached an agreement in principle regarding a license to Targa Therapeutic Payloads technologies and is engaged in licensing negotiations related to targeting moieties for its planned proprietary drugs.

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